Selective difluoroalkylation of alkenes by using visible light photoredox catalysis.
نویسندگان
چکیده
A visible light-induced process for selective difluoroalkylation of unactivated alkenes has been developed. The choice of base is crucial for governing the chemoselectivity of the process to produce difluoroalkylated alkanes and alkenes.
منابع مشابه
Visible-light-induced hydroalkoxymethylation of electron-deficient alkenes by photoredox catalysis.
Hydroalkoxymethylation of electron-deficient alkenes using alkoxymethyltrifluoroborates by photoredox catalysis has been developed. Highly reactive alkoxymethyl radicals can be easily generated from oxidation of alkoxymethyltrifluoroborates via a visible-light-induced SET process.
متن کاملDual gold and photoredox catalysis: visible light-mediated intermolecular atom transfer thiosulfonylation of alkenes.
Regioselective difunctionalization of alkenes has attracted significant attention from synthetic chemists and has the advantage of introducing diverse functional groups into vicinal carbons of common alkene moieties in a single operation. Herein, we report an unprecedented intermolecular atom transfer thiosulfonylation reaction of alkenes by combining gold catalysis and visible-light photoredox...
متن کاملVisible-light photoredox catalysis enabled bromination of phenols and alkenes
A mild and efficient methodology for the bromination of phenols and alkenes has been developed utilizing visible light-induced photoredox catalysis. The bromine was generated in situ from the oxidation of Br(-) by Ru(bpy)3 (3+), both of which resulted from the oxidative quenching process.
متن کاملVisible-light-induced synthesis of a variety of trifluoromethylated alkenes from potassium vinyltrifluoroborates by photoredox catalysis.
A facile synthesis of trifluoromethylated alkenes by the radical-mediated trifluoromethylation of vinyltrifluoroborates has been developed. Togni's reagent serves as a CF(3) radical precursor in the presence of the photoredox catalyst [Ru(bpy)(3)](PF(6))(2) under visible light irradiation. This new photocatalytic protocol can be applicable to a wide variety of vinylborates containing electronic...
متن کاملDual gold and photoredox catalysis: visible light-mediated intermolecular atom transfer thiosulfonylation of alkenes† †Electronic supplementary information (ESI) available. CCDC 1494115 for 3n and 1494114 for 3s. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc05093j Click here for additional data file. Click here for additional data file.
Regioselective difunctionalization of alkenes has attracted significant attention from synthetic chemists and has the advantage of introducing diverse functional groups into vicinal carbons of common alkene moieties in a single operation. Herein, we report an unprecedented intermolecular atom transfer thiosulfonylation reaction of alkenes by combining gold catalysis and visible-light photoredox...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 50 85 شماره
صفحات -
تاریخ انتشار 2014